![]() ![]() Local & Surface anesthesia, Topical Local Anesthetics The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers.Ģ.5%+2.5%, 2%, 1%, 1 gm/100gm, 4%, 5%, 10mg/ml,, 3%, 1.8%, 0.5%, 5%emollients, 2.5%, 2% + 2.5% + 4%, 0.025% + 2.5% + 10% + 25%, 0.0325% + 4% + 10% + 27.5%, 0.0375% + 4% + 10% + 20%Ĭream, Injection, Solution, Ointment, Lotion, Spray, Oral Solution, Intradermal, Ophthalmic, Topical Application, Injectable Solution, Intravenous Solution, Topical Cream, Topical Film, Topical Gel, Topical Gel With Applicator, Topical Kit, Topical Liquid, Topical Lotion, Topical Ointment, Topical Solution, Topical Spray, Topical Prilocaine acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. After absorption, lidocaine may cause stimulation of the CNS followed by depression and in the cardiovascular system, it acts primarily on the myocardium where it may produce decreases in electrical excitability, conduction rate, and force of contraction. ![]() In addition to blocking conduction in nerve axons in the peripheral nervous system, lidocaine has important effects on the central nervous system and cardiovascular system. This facilitates an anesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their generation in the first place. ![]() As a result, with sufficient blockage, the membrane of the postsynaptic neuron will ultimately not depolarize and will thus fail to transmit an action potential. The resultant lidocaine cations are then capable of reversibly binding the sodium channels from the inside, keeping them locked in an open state that prevents nerve depolarization. At these channels, neutral uncharged lidocaine molecules diffuse through neural sheaths into the axoplasm where they are subsequently ionized by joining with hydrogen ions. In particular, the lidocaine agent acts on sodium ion channels located on the internal surface of nerve cell membranes. ![]() It does so by stabilizing the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. It is used to provide local anesthesia by nerve blockade at various sites in the body. Lidocaine is a local anesthetic of the amide type. Lidocaine is also used to associated treatment for these conditions: Acute Otitis Media, Anal Fissures, Anorectal discomfort, Arrhythmia, Back Pain Lower Back, Bacterial Vaginosis (BV), Burns, Cervical Syndrome, Earache, Hemorrhoids, Infection, Inflammatory Reaction caused by ear infection-not otherwise specified, Insect Bites, Joint Pain, Mixed Vaginal Infections, Multiple Myeloma (MM), Myringitis, Neuritis, Osteolysis caused by Bone Tumors, Osteoporosis, Otitis Externa, Pain caused by ear infection-not otherwise specified, Pain, Inflammatory, Post-Herpetic Neuralgia (PHN), Postherpetic Neuralgia, Primary Hyperparathyroidism, Rheumatic Diseases, Rheumatic Joint Disease, Sciatica, Skin Irritation, Soft Tissue Inflammation, Sore Throat, Sunburn, Susceptible infections, Trichomonas Vaginitis, Ulcers, Leg, Urethral Strictures, Vulvovaginal Candidiasis, Abrasions, Anal discomfort, Arrhythmia of ventricular origin, Cutaneous lesions, Gum pain, Minor burns, Superficial Wounds, Susceptible Bacterial Infections, Ulceration of the mouth, Viral infections of the external ear canal, Post Myocardial Infarction Treatment, Regional Anesthesia, Local anesthesia therapyLocal anesthesia therapy Indicated as a topical anesthetic for use on normal intact skin for local analgesia, genital mucous membranes for superficial minor surgery and as pretreatment for infiltration anesthesia ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |